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The ACORN Trial was randomized clinical trial to understand the effect of empiric antibiotic choice for patients in the ED and ICU. The trial it'll only hurt for a second #shorts The ACORN Trial: Does the use of cefepime or piperacillin-tazobactam affect the risks of AKI or neurologic dysfunction in adults
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Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial. JAMA. 2023 Oct 24;330(16):1557-1567. The ACORN trial, enrolling over 2,500 patients, compared piperacillin-tazobactam (n=1,297) and cefepime (n=1,214) for empiric antibiotic
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